
The McCarty group - Spring 2023


Group hike to celebrate Alden's graduation - Spring 2023

The McCarty group - Summer 2022
Celebrating Christian, Kayla, and Josue graduating - Spring 2022


Mini golf and pizza! - Fall 2022

Kyle giving Dr. McCarty a face full of pie at the annual Chemistry Department picnic. He won the raffle with $1 - Spring 2022
Hot-Pot celebration for Kyle's defense of thesis and graduation from the Master's program in Chemistry at WWU. - Summer 2023
Group Members

Principal Investigator
James (Jay) McCarty
email: jay.mccarty@wwu.edu
Assistant Professor, Department of Chemistry
Biography
I received my B.S. in biochemistry from the California Polytechnic State University in San Luis Obispo, California, and my Ph.D. in physical chemistry from the University of Oregon. I completed my dissertation under Marina Guenza where my research focused on developing a novel coarse-graining and multi-scale modeling theory for computer simulations of complex macromolecular fluids. While at Oregon, I was also involved in the Science Literacy Program, which is aimed at improving the scientific awareness and general scientific knowledge of non-science majors at the university.
Following graduate school, I worked as a postdoctoral fellow in the research group of Michele Parrinello at ETH Z​ürich and Università della Svizzera italiana (USI) in Lugano, Switzerland. My work in the Parrinello group focused on the development of enhanced sampling methods for studying rare events from atomistic simulations, which I applied to study phase transitions in ionic solids, protein conformational changes, and chemical reaction kinetics. Prior to my current appointment at Western, I held a joint postdoctoral appointment in the research groups of professor Joan-Emma Shea in the Department of Chemistry and Biochemistry and professor Glenn H. Fredrickson in the Materials Research Laboratory at the University of California Santa Barbara. My research at UCSB involved using computational methods based on polymer field theory to study the liquid-liquid phase separation of intrinsically disordered proteins.
Currently, my interests lie in the broad field of soft condensed matter and biophysics, where I am interested in applying statistical mechanics to study the structure and dynamics of macromolecules using molecular simulations.
For more information about current projects, please visit our research page. My academic CV can be found here, along with a list of publications. (For an updated list of publications, please refer to my Google Scholar page). Also, feel free to check out my github page or profile on Research gate.
To see how I am academically related to Enrico Fermi and others, check out my academic family tree.
Graduate Students
Raphael Marcenac (2024 - present)
Raphael joined the group as a M.S. student in Chemistry in the Fall 2024. He is working on studying the segmental dynamics of a sizable intrinsically disordered region (IDR) of the plant villin 4 protein from Arabidopsis thaliana that mediates actin filament bundling in plants. His research uses a combination of molecular dynamics (MD) simulation, Markov State models (MSM), and NMR experiments to study how the IDR interacts with the folded headpiece domain resulting in segmental motion of its backbone dynamics. Characterizing the conformational states and backbone dynamics of plant villin 4 protein would advance our understanding of the biophysics of cytoskeleton regulators with large IDRs.
Undergraduate Students
Trevor Zanella (2026 - present)
Daniel Kennerud (2025 - present)
Emperial West (2025 - present)
Landon Moshofsky (2025 - present)
Chris Duble (2025 - present)
Ray Brock (2024 - present)
Former Group Members
Carter Longstreth (B.S. Biochemistry, 2025)
Phuong Dinh (B.S. Biochemistry, 2025)
Sanail Amir - REU student from Cerritos College, CA (in lab summer of 2024)
Kayla Croney (M.S. Chemistry, 2024)
David Cummins (M.S. Chemistry, 2024)
Amir Shahzad (B.S. Biology- General Biology, 2023)
Kyle Whitham (M.S. Chemistry, 2023)
Alden Harris (B.S. Biology- Molecular and Cell, 2023)
Isabelle Kim (B.A. Biochemistry, 2022)
Kayla Croney (B.S. Biochemistry, 2021)
Clarissa Huisman - REU student from Simpson College, IA (in lab summer of 2022)
Christian Phillips (B.S. Chemistry, 2021)
Josué Claros (B.S. Biochemistry, 2021)
Edwin Enciso (M.S. Chemistry, 2021)
Cass Leonard (B.S. Biochemistry, 2020)